This is a solid come back fight for both fighters though I see it as more of an opportunity for Medina as Adames is the more known fighter who has fought for a world title already.
Carlos Adames was expected to win his last fight however got upset by Patrick Teixeira in what was a great performance from the Brazilian underdog. Adames is still a skilled fighter with power and has already proven hes fringe world level.
Bryan Medina is a decent fighter but in my opinion doesn’t do anything better than Adames and hasn’t faced the same level of competition.

I think Carlos Adames will win by stoppage due to facing the better competition and also having the better skill set of power and boxing fundamentals.