This should be a highly entertaining fight but also one where in my mid theres only one winner. Josesito Lopez has looked good recently in a loss versus Keith Thurman and more recently a win over John Molina Jr. Santana hasn’t been all that active in recent years and is coming off a beating from Jarrett Hurd.
Both fighters aren’t the greatest defensively but Lopez does at least try not to eat every punch thrown at him while Santana doesn’t seem to care if he gets punched. I think Lopez is better technically and has also fought the bigger names. I think Santana doesn’t have much left in the tank even though he is the younger fighter.

I think Josesito Lopez will win a decision after ten rounds due to being slightly fresher and having better technical and defensive skills.